Search results for "Silica dust"

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Role of murine macrophages and complement in experimental campylobacter infection

1988

Summary. The roles of macrophages and the complement system as potential host defence mechanisms in mice against campylobacter infection were studied in vivo, by depleting the murine serum-complement or the phagocytic cells. Macrophage-depletion was performed by intraperitoneal (i.p.) injection of silica dust, Liquoid or dextran sulphate. During 5 days after infection, such mice showed a significant increase in mortality, compared with controls. In contrast, mice that were previously decomplemented by i.p. injection of Cobra Venom Factor showed no significant increase in mortality. The results with combined macrophage depletion and decomplementation did not differ from those with macrophage…

Microbiology (medical)PolymersVirulenceMice Inbred StrainsBiologymedicine.disease_causeMicrobiologyMicrobiologyMiceCampylobacter fetusInbred strainIn vivoCampylobacter InfectionsmedicineAnimalsElapid VenomsVirulenceMacrophagesCampylobacterComplement C3General MedicineHost defenceSilicon DioxidePolyelectrolytesComplement systemSilica dustDextran sulphateImmunologyFemaleJournal of Medical Microbiology
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P046 Occupational exposures and gastric cancer risk in the MCC-spain case-control study

2016

Objective To explore the relationship between gastric cancer (GC) and occupational exposures. Methods A total of 382 incident GC cases and 2,846 randomly selected population controls with occupational information were included from the MCC-Spain study, a population-based multicase-control study. Occupation was coded according to the Spanish National Classification of Occupations 1994. Occupational exposures were assessed by the MatEmEsp Job Exposure Matrix. ORs and their 95% confidence intervals (CI) were estimated by unconditional logistic regression adjusting for matching variables and education. Results In men, a statistically significant increased risk of GC, was found for ‘Employed ski…

education.field_of_studybusiness.industryJob-exposure matrixPopulationCase-control studyLogistic regressionConfidence intervalSilica dustIncreased riskEnvironmental healthMedicinebusinesseducationCancer riskCancer
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